Having spent most of his time studying and learning how to manipulate his reptile buddies, Venomm began using them as a weapon, building natural immunity to their venomous bites.
It's his organizational and leadership skills that make him such a formidable threat, including his stints putting together the Masters of Evil — one of the foremost groups to oppose the Avengers.
Losing his right hand to T'Chaka's son and successor, T'Challa, Klaw became one of Black Panther's most persistent antagonists, as well as battling the Fantastic Four, the Avengers, and Ka-Zar.
Over the decades, he's blurred the lines between traditional hero and villain, aligning himself with the Avengers, the Fantastic Four, and the X-Men, while also occasionally combating those same groups.
While he's traditionally considered the arch-enemy of the Fantastic Four, the good doctor has also been portrayed as an occasional enemy of Black Panther.
Seeking to avenge his parents' deaths, Killmonger became a top-ranked mercenary working for the likes of Kingpin, before journeying back to Wakanda as a revolutionary leader.