One of the most significant pieces of Marvel-related news we've learned recently is that Harrison Ford will be stepping into the role of General “Thunderbolt” Ross. Set to debut in Captain America: New World Order, Ford will inherit the role from the late great William Hurt, one of the MCU‘s earliest and most memorable antagonists.
In the most straightforward terms, the U-Foes are essentially an evil version of the Fantastic Four, having become superpowered villains after trying (and failing) to replicate the experiment that turned Reed Richards and his team into the heroes they are today.
Juggernaut has occasionally appeared in the pages of The Incredible Hulk from time to time and is one of the few villains capable of matching Hulk physically. Their battles are always epic in scope, reaping pandemonium wherever their fights end up transpiring.
Brian Banner has the unique distinction of being one of the few figures from Bruce Banner's past who crops up again as a villain of the Hulk. The biological father of Bruce, Brian Banner was an abusive alcoholic who regularly mistreated young Bruce and his mother, Rebecca.