Leaving Las Vegas (1995)
Arguably Nic Cage's most compelling role and film, Leaving Las Vegas chronicles the rapid demise of Cage's Ben Sanderson. The screenwriter flees Hollywood for Vegas, a liquor store's worth of booze in tow.
Flight (2012)
Flight is an engrossing character study of really, really high-functioning alcoholism.
A Star Is Born (2018)
One of the rare examples where a remade film is arguably better than the original, A Star Is Born features Bradley Cooper as an addict-musician Jackson Maine.
Honey Boy (2019)
This loose biopic in which LaBeouf plays his own rodeo clown, substance-abusing father, will tug at your heart and stick in your memory.
Trainspotting (1996)
Danny Boyle's masterpiece about heroin addicts bop through Edinburgh is a rare film that combines humor with drug addiction.
Rocketman (2019)
Rocketman is a thoroughly entertaining, visually-appealing film that shines a light on the rollercoaster life of an iconic showman.