Chrissy Metz has revealed that she is taking a GLP-1 medication after years of skepticism, saying concerns about her long-term health eventually persuaded her to reconsider.
The 45-year-old This Is Us star said perimenopause, obesity within her family and health problems involving her father all contributed to her decision. She discussed the treatment with her doctor and says she ultimately concluded that trying a GLP-1 could be beneficial for her.
Metz, who is now a brand ambassador for telehealth company Ro, says one of the biggest changes has been a reduction in what she calls “food noise”, the persistent thoughts about food and what she would eat next. She has also reported improvements in mobility, joint pain, inflammation, energy and blood work.
Metz began taking a GLP-1 later, in 2026, after she had already publicly discussed changing her diet, exercising and working with a trainer.
Metz Says the Medication Quieted Her ‘Food Noise’
Metz told PEOPLE that she had spent years assuming a GLP-1 either would not work for her or would produce side effects she did not want. Her experience so far has been more positive than she expected.
Metz said she had not fully realized how much mental space thoughts about food occupied until that constant preoccupation began to ease. She described being able to eat without immediately obsessing over what she would have next, after years of thinking about certain foods as inherently “bad.”
Metz also told Today that health problems involving her father contributed to her change of heart. “Maybe I should try to get ahead of it,” she recalled thinking. She ultimately said the treatment was something she believed could help her personally. “It’s not for everybody, but it’s been really wonderful for me,” Metz said.
Her Earlier GLP-1 Position Was More Complicated Than a Rejection
In August 2025, she told PEOPLE that GLP-1s brought up “very complicated feelings” for her. She expressed concern about people with restrictive eating disorders using medications that can reduce appetite, while also acknowledging that GLP-1 treatments could be important for patients with certain medical needs.
Metz also spoke about her father, who she said died from sepsis after undergoing gastric bypass surgery, and wondered whether access to GLP-1 treatment might have changed his health trajectory.
Even then, she did not rule out eventually using one herself. Her stated priority was longevity, and she said the decision to take a prescription medication was ultimately personal. Now Metz says learning more about GLP-1s, talking with her doctor and considering her own family history helped move her past some of her earlier fears.
The GLP-1 Did Not Cause the Weight Loss That Made Headlines in 2025
A 100-pound weight-loss figure circulated heavily in 2025 after Metz spoke about her health and exercise routine. She discussed becoming more consistent with strength training, working with a personal trainer and making changes to the way she ate.
PEOPLE’s current retrospective says Metz told the Daily Mail in April 2025 that she had lost 100 pounds through diet changes and exercise. Later that year, however, Metz pushed back against intense attention to the exact number.
When PEOPLE asked about reports that she had lost 100 pounds, she said, “I have lost a little weight,” and emphasized that she did not want her health journey reduced to a number on a scale.
She Says It Helps Her Through Eight Broadway Shows a Week
Metz is currently making her Broadway debut as Angélique in & Juliet, giving her an unusually physical work schedule while she adjusts to the treatment. “I can run around the stage eight shows a week,” Metz said on Today.
She said the GLP-1 has helped with inflammation, energy and her overall health while she performs as a 45-year-old woman going through perimenopause.
She continues to exercise and weight train, describing her current approach as a broader lifestyle change rather than simply taking a prescription. “It’s not the easy way out,” she said.
Metz began her limited engagement in & Juliet on June 18. She is scheduled to remain in the Broadway production through September 13.
Metz Says a GLP-1 Is ‘Not a Magic Wand’
Metz has also pushed back against the idea that taking the medication eliminates the need for other health changes. “I know it’s not a magic wand,” she told PEOPLE.
She said she continues working with a trainer, lifting weights and trying to build muscle while focusing more on strength and comfort than a particular number on the scale. Her experience is personal, and she has repeatedly stressed that she does not believe GLP-1 treatment is right for everyone.
Metz says she knew going public would bring another round of scrutiny after years of commentary about her body. She joked to PEOPLE that critics previously asked why she was not taking a GLP-1 and would now question why she had decided to use one. “My life is my life,” Metz said.